Competitors cannot have used any substances listed below during the duration periods specified. All participants are required to pass polygraph screenings prior to competitions (polygraph test results from amateur OCB and other amateur natural federations' shows can be honored for amateur OCB shows held within six weeks from the contest where testing took place. Pros must be polygraph tested for every OCB Pro show, regardless of how recently they may have been tested elsewhere). For federations other than OCB, the polygraph examiner who conducted the testing must send verification to OCB, or the examiner's name and contact information must be supplied to OCB in order for results to be honored for amateur contests). In addition to polygraph testing, pro qualifying placement winners at amateur events, and cash prize placement winners in pro divisions, must pass a urine test.

Polygraph screenings are used since events are 7 years drug-free for most substances. Most anabolic steroids and other banned substances are no longer detectable in urine within a couple of months from last use, and growth hormone is not detected in routine sports panel urine testing. Note: Approximately half who don’t pass the polygraph are bikini competitors. Certain banned substances can yield an unfair advantage in getting leaner and shapelier.

Anabolic Agents (including fragments, metabolites, and releasing factors) – Banned 7 Years

Including, but not limited to (some trade names shown in parenthesis):
1-Androstendiol
1-Androstendione
1-Testosterone
19-Norandrostenedione
4-Hydroxytestosterone
6a-Methylandrostendione
Androstendiol
Androstendione
Bolasterone
Boldenone (Equipoise)
Calusterone
Clenbuterol
Clostebol
Danazol
Dehydrochlormethyltestosterone
Desoxymethyltestosterone
DHEA (aka androstenolone) in excess of 100mg/day (Note "7-Keto-DHEA" is different than "DHEA" and is not banned)
Drostanolone
Estra-4,9-dien-3,17-dione
Fluoxymesterone
Formebolone
Formestane
Furazabol
Halodrol
Mestanolone
Mesterolone
Methandriol
Methandrostenolone (Dianabol)
Methasterone (Superdrol)
Methenolone (Primobolan)
Methyl-1-testosterone
Methyltestosterone
Mibolerone
Nandrolone (Deca-Durabolin)
Norclostebol
Norethandrolone
Oxabolone
Oxandrolone (Anavar)
Oxymesterone
Oxymetholone (Anadrol)
Prostanozol
Stanozolol
Stenbolone (Winstrol)
Testosterone
Trenbolone

Prescription-grade Stimulants and Weight-Loss Substances – Banned 6 Months

Including, but not limited to:
Amphetamines
Cocaine
Methamphetamine
Methylphenidate
Modafinil
Phentermine

Prescription-Grade Diuretics & Masking Agents Used for Competition Purposes – Banned 1 Week

Including, but not limited to:
Acetazolamide
Amiloride
Bendroflumethiazide
Bumetanide
Canrenone
Chlorothiazide
Chlorthalidone
Clopamide
Cyclothiazide
Dichlorphenamide
Ethacrynic acid
Furosemide (Lasix)
Hydrochlorothiazide (aka HCT or HCTZ)
Hydroflumethiazide
Spironolactone
Triamterene

Miscellaneous

Prescription-Grade Anti-Estrogens (including, but not limited to, Arimidex (anastrozole), Clomid, Nolvadex (tamoxifen), and hCG (human chorionic gonadotropin) (disallowed for a period of 7 years prior to an OCB event)
Synthol (disallowed for a period of 7 years prior to participation in an OCB event).
Peptide Hormones (e.g., HGH, IGF) (disallowed for a period of 7 years prior to participation in an OCB event).
Selective Androgen Receptor Modulators (SARMs) (after 12/31/15).
Growth Hormone Releasing Hormone (GHRH)/Growth Hormone-Releasing Peptides (GHRPs)/Growth Hormone Secretagogues (GHS) (after 12/31/18).

Urine test lab reports showing only a testosterone/epitestosterone (T/E) ratio above 6.0 are considered positive results for presence of banned substances and result in disqualification with a 7-year suspension, unless competitors exercise the option of having isotope ratio mass spectrometry (IRMS) analyses performed on their sample at their own expense ($450), and those results show no synthetic testosterone was detected.

Any athletes with muscle implants are considered ineligible for OCB events indefinitely.

OCB's policy on doctor prescribed testosterone